Phillip A. Sharp AKA Phillip Allen Sharp Born: 6-Jun-1944 Birthplace: Falmouth, KY
Gender: Male Race or Ethnicity: White Sexual orientation: Straight Occupation: Biologist Nationality: United States Executive summary: Eukaryotic (split) genes Molecular biologist Phillip A. Sharp discovered discontinuous genes or "split genes" in mammalian cells -- long sections of deoxyribonucleic acid (DNA) with no encoded protein structure. His discovery earned the 1993 Nobel Prize in Physiology or Medicine, shared with Richard J. Roberts, who reached the same conclusions in his own studies.
Sharp is also a man of business accomplishments, co-founder of three successful companies: Biogen (now Biogen Idec), a huge pharmaceutical, medical research, and genetic engineering conglomerate; Alnylam Pharmaceuticals, which develops ribonucleic acid (RNA)-based therapeutics; and Magen Biosciences, a company researching skin physiology. In 1995 he received a threatening letter from "FC", later identified as Unabomber Ted Kaczynski.
Father: Joseph Walter Sharp Mother: Kathrin Colvin Sharp Wife: Ann Holcombe Sharp (college sweetheart, m. 1964) Daughter: Christine Alynn (b. 1968) Daughter: Sarah Katherin (b. 1974) Daughter: Helena Holcombe (b. 1981)
High School: Pendleton High School, Falmouth, KY (1962) University: BS Chemistry & Mathematics, Union College of Kentucky (1966) University: PhD Chemistry, University of Illinois at Urbana-Champaign (1969) Scholar: Molecular Biology, California Institute of Technology (1969-71) Scholar: Cold Spring Harbor Laboratory (1971-72) Teacher: Cancer Research & Biology, Massachusetts Institute of Technology (1974-79) Professor: Molecular Biology, Massachusetts Institute of Technology (1979-) Administrator: Director of Cancer Research, Massachusetts Institute of Technology (1985-91) Administrator: Director of McGovern Institute, Massachusetts Institute of Technology (2000-04)
National Medal of Science 2004 Benjamin Franklin Medal 1999 (by the American Philosophical Society) Nobel Prize for Medicine 1993 (with Richard J. Roberts) Lasker Award 1988 Dickson Prize 1980 Alnylam Pharmaceuticals Co-founder (2002)
Biogen Co-founder (1978)
Member of the Board of Alnylam Pharmaceuticals (2002-)
Member of the Board of Biogen Idec (2003-)
Member of the Board of Biogen (1982-2003)
Member of the Board of Magen BioSciences
American Association for the Advancement of Science American Academy of Arts and Sciences American Association for Cancer Research American Chemical Society American Philosophical Society American Society for Microbiology American Society for Biochemistry and Molecular Biology Federation of American Scientists Board of Sponsors National Academy of Sciences
Official Website: http://web.mit.edu/sharplab/bio.html
Author of books:
DNA Tumor Viruses: Control of Gene Expression and Replication (1986, with Michael Botchan and Terri Grodzicker) Nuclear Processes and Oncogenes (1992)
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