| Bruce A. Beutler AKA Bruce Alan Beutler Born: 29-Dec-1957
Birthplace: Chicago, IL
Gender: Male
Race or Ethnicity: White
Sexual orientation: Straight
Occupation: Biologist Nationality: United States
Executive summary: Lipopolysaccharide receptors Fascinated with nature even as a child, Bruce A. Beutler decided at the age of seven that he would be a biologist. He graduated from the University of California at San Diego at age 18, and earned his MD at the University of Chicago. In a series of discoveries beginning in the mid-1980s, Beutler isolated tumor necrosis factor (TNF) in mice, and discovered its inflammatory properties; developed recombinant inhibitors for TNF, which are now used widely as a treatment for inflammatory diseases; and discovered the receptor for lipopolysaccharide (LPS), which helps explain how inflammatory diseases begin and how mammals sense infection. For his work with lipopolysaccharide receptors, Beutler won the Nobel Prize in Physiology or Medicine for 2011, sharing the honor with Jules A. Hoffmann and Ralph M. Steinman. Father: Ernest Beutler (hematologist, b. 1928, d. 2008)
Mother: Brondelle Fleisher (journalist, m. 1950)
Sister: Deborah Ann Beutler (physician)
Brother: Earl Bryan Beutler (software executive)
Brother: Steven Merrill Beutler (physician)
Wife: Barbara Lanzl (m. circa 1979, div. 1988)
Son: Daniel (b. 1983)
Son: Elliot (b. 1984)
Son: Jonathan (b. 1987)
High School: Polytechnic School, Pasadena, CA
University: BA, University of California at San Diego (1976)
Medical School: MD, University of Chicago (1981)
Scholar: Residency, University of Texas at Dallas
Fellow: Rockefeller University (1983-86)
Teacher: Ass't Prof. of Internal Medicine, University of Texas at Dallas (1986-1990)
Teacher: Assoc. Prof. of Internal Medicine, University of Texas at Dallas (1990-96)
Professor: Internal Medicine, University of Texas at Dallas (1996-2000)
Professor: Genetics, Scripps Research Institute (2000-present)
Professor: Genetics, University of Texas at Dallas (2011-present)
FAS Charles Leopold Mayer Prize 2006
Balzan Prize 2007, with Jules A. Hoffmann
Shaw Prize in Life Science and Medicine 2011, with Hoffmann and Ruslan Medzhitov
Nobel Prize for Medicine 2011, with Hoffmann and Ralph M. Steinman
Howard Hughes Medical Institute Assistant Investigator (1986-91)
Howard Hughes Medical Institute Investigator (1991-2000)
American Association of Immunologists
American Society for Clinical Investigation
Association of American Physicians
European Molecular Biology Organization
Institute of Medicine
International Mammalian Genome Society
National Academy of Sciences
German Ancestry Paternal
Jewish Ancestry
Ukrainian Ancestry Maternal
Official Website:
http://www.scripps.edu/research/genetics/faculty.html?name=beutl
Author of books:
Tumor Necrosis Factors (1992, non-fiction)
Immunology, Phenotype First (2007, non-fiction)
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